ADMET Services in collaboration with Pharmcore Labs
Established in 2014, PharmaCore Labs (PCL), headquartered in San Diego, CA, is a pioneering company dedicated to advancing ion channel discovery in neuroscience and cardiovascular research.
At PCL, we have developed an innovative ion channel targeted neuroscience discovery platform, which encompasses a wide range of assays from in-vitro to in-vivo studies. Our capabilities include the development of over a hundred stable cell lines for voltage and ligand gated ion channels, as well as conducting native neuron excitability tests and hiPS DRG/SN studies. Additionally, we specialize in the creation and utilization of animal disease models to further our understanding of ion channel function and dysfunction.
Moreover, our team possesses specialized expertise in:
- Preclinical cardiac safety assessment
- Comprehensive in vitro Proarrhythmia Assay (CiPA)
- Induced pluripotent stem cells (iPS)
- Action potential (AP) measurements
- GLP assessments crucial to drug development and safety evaluation